Projects

sensory role of urothelial cells Unveiling the role of urothelial cell contribution to bladder sensation and pain

Urothelial cells play an active role in bladder physiology by responding to physical/chemical stimuli and signaling to sensory neurons and other cell types in the bladder. This project broadly focuses on functionally and molecularly identify the population of sensory neurons responding to direct urothelial stimulation of sensory nerve activity in normal and inflammatory conditions.

angiotensin signaling in the bladder studying the role of local angiotensin signaling in bladder function

studying the role of local angiotensin signaling in bladder function

technology development development of technologies targeting the lower urinary tract to improve basic science and human health

Our lab works closely with material, chemical, and electrical engineers to develop new tools to study the nervous system with the end goal of using these tools to study the changes that occur in these systems during and after the development of chronic pain, as well as the hopeful end goal of implementing these strategies in patients

bladder function and spinal cord injury Development of approaches to improve bladder function following spinal cord injury

More than 17,000 Americans suffer from spinal cord injuries yearly, and many of these patients suffer from lower urinary tract dysfunction. We are working on multiple fronts to improve our understanding of how bladder function is affected by SCI and developing therapies to treat it.